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OD PERSPECTIVE

Refraction Changes and 
Vision Problems
in Children

One of the things that ECPs can count on is the fact that the human visual system will change as one ages. Myopic, hyperopic, presbyopic and astigmatic changes allow us to regularly provide the needed eye care to facilitate those changes. We are also fortunate to have products such as clear and colored plastic lenses, polycarbonate, Trivex, Transitions lenses, soft contact lenses, and gas permeable contact lenses to help those people in need. Lens treatments with ultraviolet protection or anti-reflective coating can also add a comfort level to a minus or plus prescription.

Besides refraction changes that occur throughout our lifetime, vision problems can occur due to the aging of the different anatomical structures of the human eye. There are functional developmental changes that occur as a newborn ages including the ability to determine sizes, shapes, orientation, and distances of objects. Some visual abilities are inherited, some are learned, and some are affected by one’s environment. Within hours after birth, a child can move their eyes together and make compensatory eye movements in response to head movements.

By 2 months of age accommodation and convergence can be demonstrated. There is rod and cone function in infants, although the time when color vision is actually achieved is debatable. Some experts state that color vision does not develop before the age of 4-6 months. Experts have some disagreement as to whether color vision is actually present or if this is a learned cortical/brain function which has not developed fully at this very young age.

Other researchers have stated that red, blue, and green cone functioning may be present from 7-11 weeks of age. Other changes that will occur through the growth and early maturation process include acuity and pattern vision, spatial vision, perceptual-motor skills, cognition and learning, the ability to understand language, and to read.

According to Dr. Jack Richman, “The earlier in life that deficits in visual acuity can be determined, the better are the chances in finding visual disorders that may have a harmful effect on the child’s learning and developmental process.” The National Society for the Prevention of Blindness estimates that 5% of the 3-5 year age group has vision problems, even though the eye is at an adult stage by age 3. Growth can still occur to a lesser degree after this age. The length of the eye increases from its size at birth to approximately 28 millimeters by the ages of 8 to age 13, with most of the growth reached by age 8-9. The prevalent vision disorders in the preschool population are myopia-1%, hyperopia-7%, astigmatism-2%, anisometropia-2%, and amblyopia-1.5-2%. 67% of infants show 2-3 diopters of against-the-rule astigmatism with retinoscopy but by age 1-2, the astigmatism flips to a small amount of with-the-rule astigmatism.

Perhaps the most active period for changes in the magnitude of refractive errors is during the first years of life. Large fluctuations can be seen especially in children with anisometropia or astigmatism. Studies done by Dr. Hirsch and Dr. Baldwin found that females exhibit myopia at an earlier age than males. From ages 6-11, girls have a higher mean refraction, but at age 11 the trend reverses. A higher percentage of females show refractive changes from age 6-13. At age 13-17, females were found to show less of a change towards myopia than males. At age 5-6, hyperopia increases for both females and males, but after this age hyperopia decreases more for males than for females. More females reveal myopia by ages 10-13 than males, but this number increases in males after age 13.

The presence of high myopia in premature infants was first identified with a condition called retrolental fibroplasia (retinopathy of prematurity-ROP) due to the use of high amounts of oxygen used in incubators. A study that was published in the American Journal of Ophthalmology by Dr. M.C. Fletcher and Dr. S. Brandon found that all premature infants had myopia whether they were affected by retrolental fibroplasia or not. Premature infants weighing more than 3.74 pounds had myopia ranging from 0.25 to 6 diopters. Those premature infants weighing less than 2.75 pounds had myopia ranging from 10 to 20 diopters. One of the first large-scale studies of the refraction of 370 newborn infants was done by Dr. R.C. Cook and Dr. R.E. Glassock and was also published in the American Journal of Ophthalmology. The refractive error findings were diverse, ranging from 11-12 diopters of myopia to 11-12 diopters of hyperopia.

Eye care professionals have always known that myopia was determined by the axial length of the eye combined with a possibly steep cornea or crystalline lens. But new research at the Ohio State University College of Optometry is finding that myopia develops in children when the crystalline lens stops adapting to the eye’s continued growth. According to Dr. Donald Mutti, “this work is trying to show that it is not just about the length of the eye, it is how the length of the eye relates to the rest of the eye. The onset of myopia is really a sudden occurrence of an imbalance between the growth of the eye and the development of the crystalline lens.”

This research was published in the March issue of Optometry and Vision Science. Dr. A. Sorsby, Dr. B. Benjamin, and Dr. M. Sheridan concluded that the growth of the eye during infancy is extremely rapid. The length of the globe increases 5 mm from 18-23 mm between birth and age 3. Between the ages of 3 and 13, the increase in axial length averages about 0.1 mm per year. In studies done of 333 school children age 6-8, Dr. G. Kemph, Dr. S. Collins, and Dr. B. Jarman found that the great majority of children are emmetropic. The refractive error distribution of this age group was 2 diopters of myopia to 3.75 diopters of hyperopia with a peak incidence of 1 diopter of hyperopia.

In a study published in the American Journal of Optometry, Dr. M.J. Hirsch concluded that “if a child has any myopia at all at ages 5-6, the myopia will be sure to remain and will probably increase. If a child has hyperopia in excess of +1.50 diopters at age 5-6, that child will very likely remain hyperopic by ages 13-14. If a child has a spherical refraction between +0.50 and +1.25 diopters, there is a great chance of being emmetropic by age 13-14. If a child has a spherical refraction between 0 and +0.50 diopters at age 5-6, then there is a high probability of becoming myopic by age 13-14. This probability becomes even greater if against-the-rule astigmatism is present.”

In another study, Dr. Hirsch found that the percentage of children having with-the-rule astigmatism was 16-20% for all age groups. The percentage of those children having against-the-rule astigmatism increased from 3-11% during their school years. In a study done by Dr. Matsumura and Dr. Hirai of Japanese students age 3-17, the prevalence of myopia increased from 43.5% at age 12 to 66.0% by age 17.

Their results showed a considerable increase in the incidence of myopia among those 7 years of age or older and there was a greater shift towards myopia especially in students older than 10 years of age. Other studies done showed a considerable increase in the incidence of myopia among those 7 years of age or older, and changes in mean refractive errors also demonstrated a greater shift toward myopia, especially in students older than 10 years. Also, the prevalence of myopia increased from 49.3% to 65.6% in 17-year-old students.

The National Center for Health Care Statistics states that other eye problems in this age group include inflammation, eye injuries, allergy problems, strabismus, congenital disorders, convergence and divergence problems, tropias, and amblyopia. Medical eye problems that may require special attention and higher levels of primary, secondary, and tertiary eye care include blocked tear ducts, Sturge-Weber’s syndrome, ptosis, congenital cataracts, and congenital glaucoma. Red eyes, conjunctivitis, projectile eye injuries, sports injuries, and blepharitis are commonly seen by eye care professionals.

Serious problems include children affected by HIV, juvenile rheumatoid arthritis, juvenile diabetes, juvenile hypertension, retinoblastoma, toxocariasis, crack/cocaine affected children born to addicted parents, fetal alcohol children born to alcoholic parents, learning disabled children including autistic and Down’s Syndrome children, children born with birth defects or other chromosomal anomalies, hyperactive or emotionally challenged children, hearing impaired children, dyslexic children, and children with seizure disorders, Lupus erythematous, multiple sclerosis, Guillan-Barre syndrome, Stevens-Johnson syndrome, malnutrition problems and color vision problems.

As ECPs we should remember that this population group may need special attention in order to prevent a lifetime visual disability. Statistics and data are important in allowing us to have a guide as to what to expect in a certain population group. No matter what the age of any patient, each patient has their own unique needs, identities, personalities, and characteristics. This is why our jobs are rewarding and challenging. And we are fortunate to have the opportunity to meet those challenges as well as to reap the rewards professionally.

Jason Smith
OD, MS

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